Mas-Sandoval A, Arauna LR, Gouveia MH, Barreto ML, Horta BL, Lima-Costa MF, Pereira AC, Salzano FM, Hünemeier T, Tarazona-Santos E, Bortolini MC, Comas D (2019) Reconstructed Lost Native American Populations from Eastern Brazil Are Shaped by Differential Jê/Tupi Ancestry. Genome Biol Evol. 11(9):2593–2604.PMID: 31328768.
Lobo‐Alves S, Augusto D, Magalhães W, Tarazona‐Santos E, Lima‐Costa M, Barreto M, Horta B, Almeida R, Petzl‐Erler M (2019) Long noncoding RNA polymorphisms influence susceptibility to endemic pemphigus foliaceus. Br J Dermatol. 181:324-331.PMID: 30653253.
da Silva TM, Fiaccone RL, Kehdy FSG, Tarazona-Santos E, Rodrigues LC, Costa GNO, Figueiredo CA, Dos Santos DN, Feitosa CA, Fattore GL, Santos LM, Alcantara-Neves NM, Cruz ÁA, Barreto ML (2019) African biogeographical ancestry, atopic and non‐atopic asthma and atopy: A study in Latin American children. Pediatr Pulmonol. 54:125–132.PMID: 30548437.
Oliveira P, Costa GNO, Damasceno AKA, Hartwig FP, Barbosa GCG, Figueiredo CA, Ribeiro-Silva RC, Pereira A, Lima-Costa MF, Kehdy FS, Tarazona-Santos E, Horta BL, Rodrigues LC, Fiaccone RL, Barreto ML (2019) Genome-wide burden and association analyses implicate copy number variations in asthma risk among children and young adults from Latin America. Sci Rep. 8(1):14475.PMID: 30262839.
2018
Lima‐Costa MF, Gouveia MH, Cesar CC, Tarazona‐Santos E, Stewart R, Ferri CP, Castro‐Costa E (2018) Genomic African and Native American Ancestry and 15‐Year Cognitive Trajectory: Bambui Study, Brazil. J Am Geriatr Soc. 66:1956-1962.PMID: 30221750.
Magalhães WCS, Araujo NM, Leal TP, Araujo GS, Viriato PJS, Kehdy FS, Costa GN, Barreto ML, Horta BL, Lima-Costa MF, Pereira AC, Tarazona-Santos E, Rodrigues MR, Brazilian EPIGEN Consortium (2018) EPIGEN-Brazil Initiative resources: a Latin American imputation panel and the Scientific Workflow. Genome Res. 28(7):1090-1095.PMID: 29903722.
Rodrigues-Soares F, Kehdy FSG, Sampaio-Coelho J, Andrade PXC, Zolini C, Aquino MM, Barreto, ML, Horta BL, Pereira AC, Llerena A, Tarazona-Santos E (2018) Genetic structure of pharmacogenetic biomarkers in Brazil inferred from a systematic review and population-based cohorts: a RIBEF/EPIGEN-Brazil initiative. Pharmacogenomics J. 18:749–759.PMID: 29713005.
da Silva TM, Fiaccone RL, Kehdy FSG, Tarazona-Santos E, Rodrigues LC, Costa GNO, Figueiredo CA, Alcantara-Neves NM, Barreto ML (2018) Biogeographical ancestry is associated with socioenvironmental conditions and infections in a Latin American urban population. SSM Popul Health. 4:301-306.PMID: 29854914.
Horta BL, Victora CG, França GVA, Hartwig FP, Ong KK, Rolfe EL, Magalhães EIS, Lima NP, Barros FC (2018) Breastfeeding moderates FTO related adiposity: a birth cohort study with 30 years of follow-up.Sci Rep 8(1):2530.PMID: 29416098.
Torres KCL, Rezende VB, Lima-Silva ML, Santos LJS, Costa CG, Mambrini JVM, Peixoto SV, Tarazona-Santos E, Martins Filho OA, Lima-Costa MF, Teixeira-Carvalho A (2018) Immune senescence and biomarkers profile of Bambuí aged population-based cohort. Exp Gerontol. 103:47-56.PMID: 29247791.
Medina-Gomez C et al.(2018) Life-Course Genome-wide Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects. Am J Hum Genet. 102(1):88-102.PMID: 29304378.
Sung YJ et al. (2018) A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. Am J Hum Genet. 102(3):375-400.PMID: 29455858.
Burkart KM et al. (2018) A Genome-wide Association Study in Hispanics/Latinos Identifies Novel Signals for Lung Function. The Hispanic Community Health Study/Study of Latinos. Am J Respir Crit Care Med.Feb 2.PMID: 29394082.
2017
Sofer T, Wong Q, Hartwig FP, Taylor K, Warren HR, Evangelou E, Cabrera CP, Levy D, Kramer H, Lange LA, Horta BL; COGENT-BP consortium, Kerr KF, Reiner AP, Franceschini N (2017) Genome-Wide Association Study of Blood Pressure Traits by Hispanic/Latino Background: the Hispanic Community Health Study/Study of Latinos. Sci Rep. 7(1):10348.PMID: 28871152.
Queiroz GA, Costa RS, Alcantara-Neves NM, Nunes de Oliveira Costa G, Barreto ML, Carneiro VL, Figueiredo CA (2017) IL33 and IL1RL1 variants are associated with asthma and atopy in a Brazilian population. Int J Immunogenet. 44(2):51-61.PMID: 28266165.
Fiuza BSD, Silva MJ, Alcântara-Neves NM, Barreto ML, Costa RDS, Figueiredo CA (2017) Polymorphisms in DENND1B gene are associated with asthma and atopy phenotypes in Brazilian children. Mol Immunol. 90:33-41.PMID: 28668455.
Marques CR, Costa GN, da Silva TM, Oliveira P, Cruz AA, Alcantara-Neves NM, Fiaccone RL, Horta BL, Hartwig FP, Burchard EG, Pino-Yanes M, Rodrigues LC, Lima-Costa MF, Pereira AC, Gouveia MH, Sant Anna HP, Tarazona-Santos E, Lima Barreto M, Figueiredo CA (2017) Suggestive association between variants in IL1RAPL and asthma symptoms in Latin American children. Eur J Hum Genet. (4):439-445.PMID: 28120837.
Lima-Costa MF, Mambrini JVM, Torres KCL, Peixoto SV, Andrade FB, De Oliveira C, Tarazona-Santos E, Teixeira-Carvalho A, Martins-Filho OA (2017) Multiple inflammatory markers and 15-year incident ADL disability in admixed older adults: The Bambui-Epigen Study. Arch Gerontol Geriatr. 72:103-107.PMID: 28618322.
Lima-Costa MF, Melo Mambrini JV, Lima Torres KC, Peixoto SV, de Oliveira C, Tarazona-Santos E, Teixeira-Carvalho A, Martins-Filho OA (2017) Predictive value of multiple cytokines and chemokines for mortality in an admixed population: 15-year follow-up of the Bambui-Epigen (Brazil) cohort study of aging. Exp Gerontol. 98:47-53.PMID: 28803133.
Schmidt AF (2017) PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study. Lancet Diabetes Endocrinol. (2):97-105.PMID: 27908689.
Lima-Costa MF, Macinko J, Mambrini JV, Peixoto SV, Pereira AC, Tarazona-Santos E, Ribeiro AL (2016) Genomic African and Native American Ancestry and Chagas Disease: The Bambui (Brazil) Epigen Cohort Study of Aging. PLoS Negl Trop Dis. 10(5):e0004724.PMID: 27182885.
Loret de Mola C, Hartwig FP, Gonçalves H, Quevedo Lde A, Pinheiro R, Gigante DP, Motta JV, Pereira AC, Barros FC, Horta BL (2016) Genomic ancestry and the social pathways leading to major depression in adulthood: the mediating effect of socioeconomic position and discrimination. BMC Psychiatry 16(1):308.PMID: 27596337.
Tarazona-Santos E, Kehdy F, Magalhães WCS, Rodrigues MR, Scliar M, Zolini C, Barreto ML, Horta BL, Pereira AC, Lima-Costa MF (2016) Brasil e a idiossincrasia da miscigenação. Revista UFMG 22(1-2):232-249, Belo Horizonte.
Lima-Costa MF, Mambrini JM, Leite MLC, Peixoto SV, Firmo JO, Loyola AI, Gouveia M, Leal TP, Pereira A, Macinko J, Tarazona- Santos E. Socioeconomic position, but not African genomic ancestry, is associated with blood pressure in the Bambui-Epigen (Brazil) Cohort Study of Ageing. Hypertension 2016 Feb;67(2):349-55.PMID:26711733.
Borges MC, Hartwig FP, Oliveira IO, Horta BL. (2016) Is there a causal role for homocysteine concentration in blood pressure? A Mendelian randomization study. Am J Clin Nutr. Jan;103(1):39-49.PMID:26675774.
Hartwig FP, Horta BL, Smith GD, de Mola CL, Victora CG. (2016) Association of lactase persistence genotype with milk consumption, obesity and blood pressure: a Mendelian randomization study in the 1982 Pelotas (Brazil) Birth Cohort, with a systematic review and meta-analysis. Int J Epidemiol. May 11. pii: dyw074. [Epub ahead of print] PMID:27170764.
Lima-Costa MF, Macinko J, Mambrini JV, Cesar CC, Peixoto SV, Magalhães WC, Horta BL, Barreto M, Castro-Costa E, Firmo JO, Proietti FA, Leal TP, Rodrigues MR, Pereira A, Tarazona-Santos E. Genomic Ancestry, Self-Rated Health and Its Association with Mortality in an Admixed Population: 10 Year Follow-Up of the Bambui-Epigen (Brazil) Cohort Study of Ageing. PLoS One. 2015 Dec 17;10(12):e0144456. PMID:26680774.
Costa GN, Dudbridge F, Fiaccone RL,Silva TM, Conceicao JS, Strina A, Figueiredo CA, Magalhaes WCS, Rodrigues MR, Gouveia M, Kehdy F, Horimoto A, Lessa-Horta B, Burchard E, Pino-Yanes M, Del-Rio-Navarro B, Romieu I, Hancock D, London S, Lima-Costa MF, Pereira A, Tarazona E, Rodrigues LC, Barreto M. A genome-wide association study of asthma symptoms in Latin American children. BMC Genetics (Online), v. 16, p. 141, 2015. PMID:26635092.
Kehdy FS, Gouveia MH, Machado M, Magalhães WC, Horimoto AR, Horta BL, Moreira RG, Leal TP, Scliar MO, Soares-Souza GB, Rodrigues-Soares F, Araújo GS, Zamudio R, Sant Anna HP, Santos HC, Duarte NE, Fiaccone RL, Figueiredo CA, Silva TM, Costa GN, Beleza S, Berg DE, Cabrera L, Debortoli G, Duarte D, Ghirotto S, Gilman RH, Gonçalves VF, Marrero AR, Muniz YC, Weissensteiner H, Yeager M, Rodrigues LC, Barreto ML, Lima-Costa MF, Pereira AC, Rodrigues MR, Tarazona-Santos E; Brazilian EPIGEN Project Consortium. (2015). Origin and dynamics of admixture in Brazilians and its effect on the pattern of deleterious mutations. Proc Natl Acad Sci U S A. Jul 14;112(28):8696-701. PMID: 26124090.
Lima-Costa MF, Rodrigues LC, Barreto ML, Gouveia M, Horta BL, Mambrini J, Kehdy FSG, Pereira AC, Rodrigues-Soares F, Victora CG, Tarazona-Santos E, Epigen-Brazil group. (2015). Genomic ancestry and ethnoracial self-classification based on 5,871 community-dwelling Brazilians (The Epigen Initiative). Scientific Reports 5:9812. PMID:25913126.
Santos HC, Horimoto AV, Tarazona-Santos E, Rodrigues-Soares F, Barreto ML, Horta BL, Lima-Costa MF, Gouveia MH, Machado M, Silva TM, Sanches JM, Esteban N, Magalhaes WC, Rodrigues MR, Kehdy FS, Pereira AC. A minimum set of ancestry informative markers for determining admixture proportions in a mixed American population: the Brazilian set. Eur J Hum Genet. 2015 Sep 23. PMID:26395555.
About:
The Project
The Cohorts
The Data
Research Centers:
Fiocruz
Incor
UFBA
UFMG
UFPel
Funding:
CAPES
FINEP
Decit/SCTIE/MS
CT-Saúde/FNDCT